Pentadeca Arginine Glycine (PEG-MGF)
healing-and-recovery
Verified
Mechano Growth Factor (MGF) is a splice variant of IGF-1 that is produced locally in muscle tissue in response to mechanical stress. PEGylated MGF has enhanced stability and prolonged half-life for improved tissue repair.
Chemical Information
Source:
PEGylated synthetic peptide based on the C-terminal portion of the IGF-1Ec splice variant (Mechano Growth Factor).
Clinical Information
Purposes:
Muscle repair
Recovery enhancement
Tissue regeneration
Athletic recovery
Dosing:
Typical dosing is 200-400mcg via intramuscular injection at the site of injury, 2-3 times weekly.
Related Peptides:
IGF-1 LR3
BPC-157
TB-500
Safety Information
Side Effects:
- Injection site pain
- Hypoglycemia
- Joint pain
- Water retention
Contraindications:
- Active malignancy
- Pregnancy or breastfeeding
- Diabetes (use with caution)
Research & References
- Goldspink G, et al. Mechano growth factor: a splice variant of IGF-1 that promotes muscle growth and repair. J Muscle Res Cell Motil. 2004;25(2):113-21.
- Hill M, et al. The expression and splicing of the Mechano Growth Factor gene. Mol Cell Biol. 2003;23(20):7227-38.
- https://pubmed.ncbi.nlm.nih.gov/15549541/
Last updated: 12/20/2025 at 12:19:11 AM
Version: 1
Detailed Information
Primary Uses
Muscle repair
Recovery enhancement
Tissue regeneration
Athletic recovery
Related Peptides
IGF-1 LR3
BPC-157
TB-500
Source Information
PEGylated synthetic peptide based on the C-terminal portion of the IGF-1Ec splice variant (Mechano Growth Factor).
Last updated: December 20, 2025
Version: 1